To secrete insulin is what beta cells are made for. To do so, beta cells store insulin in granules that are released upon stimulation. This is a highly controlled process. Many signals such as blood sugar levels and hormones stimulate the beta cell. In response, beta c...

Serotonin has been around for a while as a paracrine signal in the islet. Recent studies point to a role of serotonin mainly, if not exclusively, under conditions of increased metabolic demand, such as obesity and pregnancy. We now show that serotonin is produced and r...

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Division of Endocrinology, Diabetes and Metabolism

Department of Medicine

University of Miami Miller School of Medicine

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